Tania Perez Jimenez

Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s

Tania Perez Jimenez, Katrina L. Mealey, Tamara Grubb et al. · Drug Metabolism and Disposition · 2016 · 54 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability

Stephanie E. Martinez, Jian Shi, Hao‐Jie Zhu et al. · Drug Metabolism and Disposition · 2019 · 39 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Oral Coadministration of Fluconazole with Tramadol Markedly Increases Plasma and Urine Concentrations of Tramadol and the O-Desmethyltramadol Metabolite in Healthy Dogs

Tania Perez Jimenez, Butch KuKanich, Hyun Joo et al. · Drug Metabolism and Disposition · 2018 · 19 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Identification of canine cytochrome P‐450s (<scp>CYP</scp>s) metabolizing the tramadol (+)‐M1 and (+)‐M2 metabolites to the tramadol (+)‐M5 metabolite in dog liver microsomes

Tania Perez Jimenez, Katrina L. Mealey, Darren R. Schnider et al. · Journal of Veterinary Pharmacology and Therapeutics · 2018 · 18 citations

Medicine, Pharmacokinetics, Pharmacology +16

Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug–drug interactions involving canine cytochrome P‐450, UDP‐glucuronosyltransferase, and P‐glycoprotein

Michael H. Court, Katrina L. Mealey, Neal S. Burke et al. · Journal of Veterinary Pharmacology and Therapeutics · 2023 · 17 citations · Full text

Medicine, Pharmacology, Veterinary Pharmacology +17