Xeno- and feeder-free differentiation of human pluripotent stem cells to two distinct ocular epithelial cell types using simple modifications of one method

Heidi Hongisto, Tanja Ilmarinen, Meri Vattulainen, +2

Stem Cell Research & Therapy

Small-Molecule Induction Promotes Corneal Epithelial Cell Differentiation from Human Induced Pluripotent Stem Cells

Alexandra Mikhailova, Tanja Ilmarinen, Hannu Uusitalo, +1

Stem Cell Reports

Low vision status and declining vision decrease Health-Related Quality of Life: Results from a nationwide 11-year follow-up study

Joonas Taipale, Alexandra Mikhailova, Matti Ojamo, +7

Quality of Life Research

Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture

Heidi Hongisto, Sanna Vuoristo, Alexandra Mikhailova, +4

Stem Cell Research

Embryonic Stem CellDevelopmental BiologyFeeder CellsLaminin-511 ExpressionMedicine +8

Comparison of iTRAQ and SWATH in a clinical study with multiple time points

Antti Jylhä, Janika Nättinen, Ulla Aapola, +5

Clinical Proteomics

Human pluripotent stem cell-derived limbal epithelial stem cells on bioengineered matrices for corneal reconstruction

Alexandra Mikhailova, Tanja Ilmarinen, Anjula Ratnayake, +4

Experimental Eye Research

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellEngineeringOphthalmology +11

Efficient and Scalable Directed Differentiation of Clinically Compatible Corneal Limbal Epithelial Stem Cells from Human Pluripotent Stem Cells

Heidi Hongisto, Meri Vattulainen, Tanja Ilmarinen, +2

Journal of Visualized Experiments

Regenerative MedicineTissue EngineeringScalable Directed DifferentiationInduced Pluripotent Stem CellDevelopmental Biology +13

Comparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells

Alexandra Mikhailova, Antti Jylhä, Jochen Rieck, +8

Scientific Reports

Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation

Mária Szatmári-Tóth, Tanja Ilmarinen, Alexandra Mikhailova, +8

International Journal of Molecular Sciences

ApoptosisImmunologyRpe Cell RemovalCell DeathAdult Stem Cell +20

Patient stratification in clinical glaucoma trials using the individual tear proteome

Janika Nättinen, Antti Jylhä, Ulla Aapola, +4

Scientific Reports

Translational MedicineUrologyClinical Glaucoma TrialsOcular DiseaseOphthalmology +13