Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth

Martina Rudnicki, Ghoncheh Abdifarkosh, Emmanuel Nwadozi, +7

eLife

Metabolic DisorderPathologyMetabolic RemodelingVascular DensityOxidative Stress +15

Female Mice Have Higher Angiogenesis in Perigonadal Adipose Tissue Than Males in Response to High-Fat Diet

Martina Rudnicki, Ghoncheh Abdifarkosh, Omid Rezvan, +3

Frontiers in Physiology

Leptin is a physiological regulator of skeletal muscle angiogenesis and is locally produced by PDGFRα and PDGFRβ expressing perivascular cells

Emmanuel Nwadozi, Andrew S. Ng, Anna Strömberg, +4

Angiogenesis

Developmental BiologyAngiogenesisMolecular PhysiologyPhysiological RegulatorMedicine +9

Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner

Mark Richards, Emmanuel Nwadozi, Sagnik Pal, +9

eLife

ImmunologyEc BarrierCellular PhysiologyInflammationAngiogenesis +17

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Yi Jin, Yindi Ding, Mark Richards, +21

Nature Cardiovascular Research

Forkhead BoxO transcription factors restrain exercise‐induced angiogenesis

Dara Slopack, Emilie Roudier, Sammy T. K. Liu, +3

The Journal of Physiology

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Elin Sjöberg, Marit M. Melssen, Mark Richards, +11

Journal of Clinical Investigation

Endothelial Phospholipase CγImmunologyRenal InflammationImmune RegulationAntitumor Immunity +21

Muscle-derived vascular endothelial growth factor regulates microvascular remodelling in response to increased shear stress in mice

Cassandra Uchida, Emmanuel Nwadozi, Adam Hasanee, +3

Acta Physiologica

Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high‐fat diet

Emmanuel Nwadozi, Emilie Roudier, Eric Rullman, +4

The FASEB Journal

Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions

Martina Rudnicki, Alexandra Pislaru, Omid Rezvan, +6

iScience