Maksymilian Prondzynski

Differentiation of cardiomyocytes and generation of human engineered heart tissue

Kaja Breckwoldt, David Letuffe-Brenière, Ingra Mannhardt et al. · Nature Protocols · 2017 · 265 citations

Regenerative Medicine, Tissue Engineering, Cardiac Muscle +14

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

Diogo Mosqueira, Ingra Mannhardt, Jamie R. Bhagwan et al. · European Heart Journal · 2018 · 242 citations · Full text

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

Marc D. Lemoine, Ingra Mannhardt, Kaja Breckwoldt et al. · Scientific Reports · 2017 · 184 citations · Full text

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Maksymilian Prondzynski, Marc D. Lemoine, Antonia T.L. Zech et al. · EMBO Molecular Medicine · 2019 · 119 citations · Full text

Evaluation of MYBPC3 trans -Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes

Maksymilian Prondzynski, Elisabeth Krämer, Sandra D. Laufer et al. · Molecular Therapy — Nucleic Acids · 2017 · 104 citations · Full text

Cardiac Muscle, Genetics, Hcm Cells +20