John-Mark Fitzpatrick

MyD88-dependent and -independent signalling via TLR3 and TLR4 are differentially modulated by Δ9-tetrahydrocannabinol and cannabidiol in human macrophages

John-Mark Fitzpatrick, Eleanor Minogue, Lucy Curham et al. · Journal of Neuroimmunology · 2020 · 62 citations

Inflammation, -Independent Signalling, Molecular Immunology +15

Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis

Tadhg Crowley, John-Mark Fitzpatrick, Teun Kuijper et al. · Frontiers in Cellular Neuroscience · 2015 · 56 citations · Full text

Immune Regulation, Immunology, Therapeutic Effects +25

Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity

Joseph Damstra‐Oddy, Eleanor C. Warren, Christopher J. Perry et al. · British Journal of Pharmacology · 2020 · 22 citations · Full text

Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis

John-Mark Fitzpatrick, Becky Hackett, Lisa Costelloe et al. · Molecules · 2022 · 11 citations · Full text