Lukasz J. Bugaj

Optogenetic protein clustering and signaling activation in mammalian cells

Lukasz J. Bugaj, Atri T Choksi, Colin K Mesuda et al. · Nature Methods · 2013 · 489 citations

Optogenetic Protein Clustering, Signal Transduction, Medicine +4

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats

Jae Hyung Kim, Lukasz J. Bugaj, Young Jun Oh et al. · Journal of Applied Physiology · 2009 · 237 citations · Full text

Aging, Redox Biology, Nos Coupling +20

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway

Lukasz J. Bugaj, Amit J. Sabnis, Amir Mitchell et al. · Science · 2018 · 162 citations

High-throughput multicolor optogenetics in microwell plates

Lukasz J. Bugaj, Wendell A. Lim · Nature Protocols · 2019 · 130 citations

Photonics, Photonic Sensor, Optical Materials +8

Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal

Hanadie Yousef, Michael J. Conboy, Adam Morgenthaler et al. · Oncotarget · 2015 · 116 citations · Full text