A Highly Sensitive A-Kinase Activity Reporter for Imaging Neuromodulatory Events in Awake Mice

Lei Ma, Bart C. Jongbloets, Wei-Hong Xiong, +7

Neuron

Molecular NeuroscienceMolecular PhysiologySignal TransductionNeurophysiologyAwake Mice +13

Live Imaging of Endogenous PSD-95 Using ENABLED: A Conditional Strategy to Fluorescently Label Endogenous Proteins

Dale A. Fortin, Shane Tillo, Guang Yang, +9

Journal of Neuroscience

Molecular BiologyNeurotransmissionConditional StrategyCellular NeurobiologyLive Imaging +22

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates

Shane Tillo, Wei-Hong Xiong, Maho Takahashi, +8

Cell Reports

Proteinlipid InteractionSpecific Pka FunctionMolecular BiologyNeurotransmissionCellular Physiology +16

Locomotion activates PKA through dopamine and adenosine in striatal neurons

Lei Ma, Julian Day‐Cooney, Omar Jáidar, +5

Nature

NeurophysiologyPhysiologyNeurotransmitterStriatal NeuronsNeurotransmission +6

Sensitive genetically encoded sensors for population and subcellular imaging of cAMP in vivo

Crystian I Massengill, Landon Bayless-Edwards, César C. Ceballos, +10

Nature Methods

Tissue ImagingSignal TransductionEngineeringReporter Gene AssayMedicine +9

High-fidelity, efficient, and reversible labeling of endogenous proteins using CRISPR-based designer exon insertion

Haining Zhong, César C. Ceballos, Crystian I Massengill, +5

eLife

Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses

Aya Matsui, Cathy J. Spangler, Johannes Elferich, +7

eLife

Chemical SynapsesEngineeringMicroscopySynaptic TransmissionNeurotransmitter +14

Myristoylation alone is sufficient for PKA catalytic subunits to associate with the plasma membrane to regulate neuronal functions

Wei-Hong Xiong, Maozhen Qin, Haining Zhong

Proceedings of the National Academy of Sciences

Distinct in vivo dynamics of excitatory synapses onto cortical pyramidal neurons and parvalbumin-positive interneurons

Joshua B. Melander, Aran Nayebi, Bart C. Jongbloets, +5

Cell Reports