Jason Karch

Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis

Hadi Khalil, Onur Kanisicak, Vikram Prasad et al. · Journal of Clinical Investigation · 2017 · 913 citations · Full text

Life Sciences, Cardiology, Molecular Biology +15

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

Onur Kanisicak, Hadi Khalil, Malina J. Ivey et al. · Nature Communications · 2016 · 907 citations · Full text

Life Sciences, Cell Biology, Genetics +15

c-kit+ cells minimally contribute cardiomyocytes to the heart

Jop H. van Berlo, Onur Kanisicak, Marjorie Maillet et al. · Nature · 2014 · 799 citations · Full text

Life Sciences, Cell Biology, Physiology +12

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

John W. Elrod, Renee Wong, Shikha Mishra et al. · Journal of Clinical Investigation · 2010 · 370 citations · Full text

Life Sciences, Cardiology, Physiology +17

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

Jason Karch, Jennifer Q. Kwong, Michelle A. Sargent et al. · eLife · 2013 · 284 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17