Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

Zuzana Šišková, Daniel Justus, Hiroshi Kaneko, +8

Neuron

Synaptic PlasticityNeurodegenerative DiseasesAlzheimer's DiseaseSynaptic NeuroscienceMedicine +13

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

Josephine M. J. Stoffels, Jenny C. de Jonge, Mirjana Stancic, +10

Brain

InflammationPeripheral NervesNeurological DisorderMedicineImmunology +13

The Tau/A152T mutation, a risk factor for frontotemporal‐spectrum disorders, leads to <scp>NR</scp> 2B receptor‐mediated excitotoxicity

Jochen Martin Decker, Lars Krüger, Astrid Sydow, +4

EMBO Reports

Mendelian DisorderGenetic DisorderTau/a152t MutationPathologyRisk Factor +8

Degenerating Synaptic Boutons in Prion Disease

Zuzana Šišková, Anton Page, Vincent O’Connor, +1

American Journal Of Pathology

Synaptic PlasticityCreutzfeldt-jakob DiseaseSynaptic TransmissionGeneticsPrion Disease +2

Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology

Bryony C. Gray, Zuzana Šišková, V. Hugh Perry, +1

Neurobiology of Disease

Synaptic PlasticityAlzheimer's DiseaseSynaptic TransmissionMe7-induced Hippocampal PathologyDegenerative Disease +9

Morphological and Functional Abnormalities in Mitochondria Associated with Synaptic Degeneration in Prion Disease

Zuzana Šišková, Don Mahad, Carianne Pudney, +5

American Journal Of Pathology

Synaptic DegenerationCreutzfeldt-jakob DiseaseGeneticsFunctional AbnormalitiesDegenerative Disease +6

Fibronectin impedes “myelin” sheet-directed flow in oligodendrocytes: A role for a beta 1 integrin-mediated PKC signaling pathway in vesicular trafficking

Zuzana Šišková, Wia Baron, H. de Vries, +1

Molecular and Cellular Neuroscience

Developmental BiologySignal TransductionCell TraffickingVesicular TraffickingCell-matrix Interaction +10

Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity

Zuzana Šišková, V. Wee Yong, Anita Nomden, +3

Molecular and Cellular Neuroscience

FibrosisDevelopmental BiologySignal TransductionMmp-9 ActivityCell-matrix Interaction +8

Brain Region Specific Pre-Synaptic and Post-Synaptic Degeneration Are Early Components of Neuropathology in Prion Disease

Zuzana Šišková, Richard A. K. Reynolds, Vincent O’Connor, +1

PLoS ONE

Scrapie StrainSynaptic PlasticityNeurodegenerative DiseasesCreutzfeldt-jakob DiseaseNeuroanatomy +13

The Role of Activity in Synaptic Degeneration in a Protein Misfolding Disease, Prion Disease

Matteo Caleo, Laura Restani, Eleonora Vannini, +5

PLoS ONE

Creutzfeldt-jakob DiseaseSynaptic TransmissionMolecular BiologyNeurochemical BiomarkersAlzheimer's Disease +19