Investigating Novel Resistance Mechanisms to Third-Generation EGFR Tyrosine Kinase Inhibitor Osimertinib in Non–Small Cell Lung Cancer Patients

Zhe Yang, Nong Yang, Qiuxiang Ou, +10

Clinical Cancer Research

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types

Yongqian Shu, Xue Wu, Xiaoling Tong, +13

Scientific Reports

Comprehensive Genomic Profiling Identifies Novel Genetic Predictors of Response to Anti–PD-(L)1 Therapies in Non–Small Cell Lung Cancer

Wenfeng Fang, Yuxiang Ma, Jiani C. Yin, +11

Clinical Cancer Research

Liquid biopsies to track trastuzumab resistance in metastatic HER2-positive gastric cancer

De‐Shen Wang, Zexian Liu, Yun-Xin Lu, +17

Gut

Atorvastatin Coadministration May Increase Digoxin Concentrations by Inhibition of Intestinal P-Glycoprotein-Mediated Secretion

Rebecca A. Boyd, R. H. Stern, Barbra H. Stewart, +5

The Journal of Clinical Pharmacology

InflammationMolecular PharmacologyIntestinal P-glycoprotein-mediated SecretionBiochemistryMedicine +12

Utility of ctDNA in predicting response to neoadjuvant chemoradiotherapy and prognosis assessment in locally advanced rectal cancer: A prospective cohort study

Yaqi Wang, Lifeng Yang, Hua Bao, +16

PLoS Medicine

Genes associated with increased brain metastasis risk in non–small cell lung cancer: Comprehensive genomic profiling of 61 resected brain metastases versus primary non–small cell lung cancer (Guangdong Association Study of Thoracic Oncology 1036)

Hongsheng Wang, Qiuxiang Ou, Delan Li, +13

Cancer

Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancer

Lin Tong, Ning Ding, Xiaoling Tong, +15

Theranostics

Ultrasensitive and affordable assay for early detection of primary liver cancer using plasma cell‐free DNA fragmentomics

Xiangyu Zhang, Zheng Wang, Wanxiangfu Tang, +11

Hepatology

Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer

Swneke D. Bailey, Kinjal Desai, Ken J. Kron, +16

Nature Genetics

Breast OncologySomatic VariantEsr1 ExpressionTumor HeterogeneityGenetics +9