Concepedia

Hoi Chang Lee

HC

22

Publications

1.4K

Citations

19

H-Index

2008

Active since

Affiliations

University of Massachusetts Amherst(Current)

Northwestern University

Centre National de la Recherche Scientifique

Korea University

Tunis University

Hoi Chang Lee is an author at University of Massachusetts Amherst specializing in medicine, fertility, and public health.

ORCID

Top concepts

Publications per year

2008–2023

22

Publications

22

Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

Sook‐Young Yoon, Teru Jellerette, Ana M. Salicioni et al. · Journal of Clinical Investigation · 2008 · 321 citations · Full text

PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence

A Hachem, Jonathan Godwin, Margarida Ruas et al. · Development · 2017 · 153 citations · Full text

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

Jessica Escoffier, Hoi Chang Lee, Sandra Yassine et al. · Human Molecular Genetics · 2015 · 143 citations · Full text

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Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

Jessica Escoffier, Sandra Yassine, Hoi Chang Lee et al. · Molecular Human Reproduction · 2014 · 90 citations · Full text

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development

Sandra Yassine, Jessica Escoffier, Guillaume Martinez et al. · Molecular Human Reproduction · 2014 · 75 citations · Full text

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