Isabella Ponzanelli

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1

Metello Innocenti, Emanuela Frittoli, Isabella Ponzanelli et al. · The Journal of Cell Biology · 2003 · 266 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine

Giorgio Scita, Pierluigi Tenca, Liliana B. Areces et al. · The Journal of Cell Biology · 2001 · 136 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The eps8 Family of Proteins Links Growth Factor Stimulation to Actin Reorganization Generating Functional Redundancy in the Ras/Rac Pathway

Nina Offenhäuser, Alessandro Borgonovo, Andrea Disanza et al. · Molecular Biology of the Cell · 2003 · 135 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases

Maurizio Gianni’, Isabella Ponzanelli, Luca Mologni et al. · Cell Death and Differentiation · 2000 · 97 citations

Life Sciences, Cell Biology, Oncology +14

The Novel Synthetic Retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid (CD437) Causes Apoptosis in Acute Promyelocytic Leukemia Cells Through Rapid Activation of Caspases

Luca Mologni, Isabella Ponzanelli, Filippo Bresciani et al. · Blood · 1999 · 86 citations

Life Sciences, Cell Biology, Pharmacology +13