Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice

Karen Levy, Suchitra Natarajan, Jinghui Wang, +22

Scientific Reports

FLASH Irradiation Results in Reduced Severe Skin Toxicity Compared to Conventional-Dose-Rate Irradiation

Luis Soto, Kerriann M. Casey, Jinghui Wang, +14

Radiation Research

Surgical OncologyEngineeringRadiation EffectRadiation ExposureDermatology +16

Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism

Albert M. Li, Gregory S. Ducker, Yang Li, +13

Molecular Cancer Research

Molecular Magnetic Resonance Imaging of Angiogenesis <i>In Vivo</i> using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates

Stavros Melemenidis, Andrew Jefferson, Neil Ruparelia, +9

Theranostics

NanotherapeuticsEngineeringIron OxideBiomedical EngineeringTumor Biology +19

Multicellular Spheroids as In Vitro Models of Oxygen Depletion During FLASH Irradiation

Syamantak Khan, Maxime Bassenne, Jinghui Wang, +7

International Journal of Radiation Oncology*Biology*Physics

Multicellular SpheroidsOxygen DepletionRadiation EffectExtracellular MatrixPhotoprotection +9

Macrophages Promote Circulating Tumor Cell–Mediated Local Recurrence following Radiotherapy in Immunosuppressed Patients

Marjan Rafat, Todd A. Aguilera, Marta Vilalta, +12

Cancer Research

Endogenous Retroviral Elements Generate Pathologic Neutrophils in Pulmonary Arterial Hypertension

Shalina Taylor, Sarasa Isobe, Aiqin Cao, +27

American Journal of Respiratory and Critical Care Medicine

Design and validation of a dosimetric comparison scheme tailored for ultra-high dose-rate electron beams to support multicenter FLASH preclinical studies

Patrik Gonçalves Jorge, Stavros Melemenidis, Veljko Grilj, +22

Radiotherapy and Oncology

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

Callum Beach, David MacLean, Dominika Majorova, +31

Journal of Clinical Investigation

ImmunologyImmune RegulationImmunoeditingBiological TherapyComplement Receptor C5ar1 +21

Gold-siRNA supraclusters enhance the anti-tumor immune response of stereotactic ablative radiotherapy at primary and metastatic tumors

Yuyan Jiang, Hongbin Cao, Huaping Deng, +12

Nature Biotechnology