John D. Lapek

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Vishal Singh, Beng San Yeoh, Benoît Chassaing et al. · Cell · 2018 · 493 citations · Full text

Dysbiosis, Hepatology, In Vitro Fermentation +12

Essential metabolism for a minimal cell

Marian Breuer, Chuck Merryman, Kim S. Wise et al. · eLife · 2019 · 183 citations · Full text

Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

Kevin D. Freeman‐Cook, Robert L. Hoffman, Nichol Miller et al. · Cancer Cell · 2021 · 172 citations

Tumor Biology, Oncology, Cdk2/4/6 Inhibitor +10

Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities

John D. Lapek, Patricia Greninger, Robert Morris et al. · Nature Biotechnology · 2017 · 166 citations · Full text

Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity

Mansi Arora, Justin Moser, Timothy E. Hoffman et al. · Cell · 2023 · 158 citations

Signal Transduction, Cdk2 Inhibition, Cell Division +6