Dean C. Pavlick

Mechanisms and therapeutic implications of hypermutation in gliomas

Mehdi Touat, Yvonne Y. Li, Adam N. Boynton et al. · Nature · 2020 · 661 citations · Full text

Neuro-oncology, Medicine, Therapeutic Implications +5

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

Janice M. Mehnert, Anshuman Panda, Kim M. Hirshfield et al. · Journal of Clinical Investigation · 2016 · 382 citations · Full text

Tumor Biology, Immune Activation, Dna Polymerase Epsilon +15

Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors

Coren A. Milbury, James Creeden, Wai‐Ki Yip et al. · PLoS ONE · 2022 · 319 citations · Full text

Analytical Validation, Solid Tumors, Pathology +21

Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer

Milan Radovich, Guanglong Jiang, Bradley A. Hancock et al. · JAMA Oncology · 2020 · 292 citations · Full text

Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response

Meagan Montesion, Karthikeyan Murugesan, Dexter X. Jin et al. · Cancer Discovery · 2020 · 231 citations · Full text