ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3

Sylvia Hoff, Jan Halbritter, Daniel Epting, +38

Nature Genetics

Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease

Hao Lu, Maria C. Rondón Galeano, Elisabeth Ott, +30

Nature Genetics

Mendelian DisorderGenetic DisorderGeneticsInherited Metabolic DiseaseRenal Pathology +6

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis

Daniel Epting, Katrin Kern, Christian Dietz, +4

American Journal of Physiology-Heart and Circulatory Physiology

Vegf-driven Retinal NeovascularizationAngiogenesisSmall Gtpase RhoaRetinaReceptor Tyrosine Kinase +14

The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish

Daniel Epting, Björn Wendik, Katrin Bennewitz, +2

Circulation Research

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

Daniel Epting, Krasimir Slanchev, Christopher Boehlke, +11

Development

Multiciliated CellsXenopus Epidermal MccsCytoskeletonPlanar OrientationCellular Physiology +14

Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations

John Devane, Elisabeth Ott, Eric Olinger, +32

The American Journal of Human Genetics

Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium

Matthias Wuttke, Craig S. Wong, Elke Wühl, +18

Nephrology Dialysis Transplantation

Microridge-like structures anchor motile cilia

Takayuki Yasunaga, Johannes Wiegel, Max D. Bergen, +11

Nature Communications

A Complex of BBS1 and NPHP7 Is Required for Cilia Motility in Zebrafish

Yun Hee Kim, Daniel Epting, Krasimir Slanchev, +3

PLoS ONE

GeneticsMolecular BiologyCilia MotilityTranscription Factor Nphp7Molecular Genetics +17

Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome

Daniel Epting, Lokuliyange D. S. Senaratne, Elisabeth Ott, +27

Human Mutation

Joubert SyndromeGeneticsCby1 TranscriptPathologyDisease Gene Identification +17