A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates

Joyce Chan, Derek E. Piper, Qiong Cao, +37

Proceedings of the National Academy of Sciences

ImmunologyHyperlipidemiaNonhuman PrimatesImmunotherapyInflammation +16

Effects of Donepezil on Neuropsychiatric Symptoms in Patients With Dementia and Severe Behavioral Disorders

Jeffrey L. Cummings, Thomas McRae, Richard Zhang

American Journal of Geriatric Psychiatry

NeuropsychologyAlzheimer's DiseasePsychiatryPsychotropic MedicationDementia +12

A multinational, randomised, 12‐week study comparing the effects of donepezil and galantamine in patients with mild to moderate Alzheimer's disease

Roy Jones, Hilkka Soininen, Klaus Häger, +5

International Journal of Geriatric Psychiatry

Dose-dependent benzalkonium chloride toxicity imparts ocular surface epithelial changes with features of dry eye disease

Richard Zhang, Mijeong Park, Alexander Richardson, +6

The Ocular Surface

Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques

Philip G. Conaghan, Mikkel Østergaard, M.A. Bowes, +12

Annals of the Rheumatic Diseases

Association of <i>FADS1/2</i> Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis

Hao Yu Chen, Benjamin J. Cairns, Aeron Small, +43

JAMA Cardiology

Defective feedback regulation of NF-κB underlies Sjögren <i>’</i> s syndrome in mice with mutated κB enhancers of the <i>IκBα</i> promoter

Bailu Peng, Jianhua Ling, Andrew Joon Lee, +11

Proceedings of the National Academy of Sciences

A flexible repertoire of transcription factor binding sites and a diversity threshold determines enhancer activity in embryonic stem cells

Gurdeep Singh, Shanelle Mullany, Sakthi D. Moorthy, +6

Genome Research

Flexible RepertoireTranscriptomics TechnologyGene Regulatory NetworkCell SpecializationTfbs Sequence Diversity +17

Safety and Tolerability of Donepezil at Doses up to 20 mg/day

Rachelle S. Doody, Jody Corey‐Bloom, Richard Zhang, +3

Drugs & Aging

Drug SafetyMolecular PharmacologyTherapeutic Drug MonitoringPharmacological StudyMedicine +5

Uncovering the Protective Neurologic Mechanisms of Hypofractionated FLASH Radiotherapy

Yasaman Alaghband, Barrett D. Allen, Enikö A. Kramár, +11

Cancer Research Communications