Penny Bradley

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi et al. · The Lancet · 2020 · 5K citations · Full text

Veterinary Medicine, Infectious Diseases, Preventive Medicine +17

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi et al. · The Lancet · 2021 · 1.2K citations · Full text

Veterinary Medicine, Immunology, Immunization +16

Metformin and physical performance in older people with probable sarcopenia and physical prefrailty or frailty in England (MET-PREVENT): a double-blind, randomised, placebo-controlled trial

Miles D. Witham, Claire McDonald, Nina Wilson et al. · The Lancet Healthy Longevity · 2025 · 29 citations · Full text

Medicine, Geriatric Medicine, Pharmacotherapy +17

MET-PREVENT: metformin to improve physical performance in older people with sarcopenia and physical prefrailty/frailty – protocol for a double-blind, randomised controlled proof-of-concept trial

Katherine Rennie, Miles D. Witham, Penny Bradley et al. · BMJ Open · 2022 · 16 citations · Full text

Medicine, Geriatric Medicine, Pharmacotherapy +17

Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy

Alaa Abouhajar, Lisa Alcock, Theophile Bigirumurame et al. · Trials · 2022 · 12 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +17