Helton José Wiggers

Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay

Helton José Wiggers, Josmar R. Rocha, W.B. Fernandes et al. · PLoS neglected tropical diseases · 2013 · 86 citations · Full text

Drug Target, Antiparasitic Agent, Pathology +25

Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery

Juliana Cheleski, Josmar R. Rocha, Matheus Pinto Pinheiro et al. · European Journal of Medicinal Chemistry · 2010 · 68 citations · Full text

Aldo-keto Reductase, Aldehyde Dehydrogenase, Biochemistry +7

Effects of organic solvents on the enzyme activity of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase in calorimetric assays

Helton José Wiggers, Juliana Cheleski, Aderson Zottis et al. · Analytical Biochemistry · 2007 · 58 citations

Organic Solvents, Biochemistry, Cellular Enzymology +9

Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: Implications to tetramer stability and ligand-binding

Daniela Barretto Barbosa Trivella, Lucas Bleicher, Leonardo Palmieri et al. · Journal of Structural Biology · 2010 · 41 citations

Quercetin-Crosslinked Chitosan Films for Controlled Release of Antimicrobial Drugs

Helton José Wiggers, Pascale Chevallier, Francesco Copes et al. · Frontiers in Bioengineering and Biotechnology · 2022 · 37 citations · Full text