Randi Isaacs

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

Donald M. O’Rourke, MacLean P. Nasrallah, Arati Desai et al. · Science Translational Medicine · 2017 · 1.7K citations · Full text

Cell Therapy, Antigen Loss, Immunology +16

B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma

Adam D. Cohen, Alfred L. Garfall, Edward A. Stadtmauer et al. · Journal of Clinical Investigation · 2019 · 768 citations · Full text

Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma

Milind Javle, Maeve A. Lowery, Rachna T. Shroff et al. · Journal of Clinical Oncology · 2017 · 700 citations

Surgical Oncology, Pathology, Phase Ii Study +17

Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study

Lucia Nogová, Lecia V. Sequist, José Manuel Pérez García et al. · Journal of Clinical Oncology · 2017 · 419 citations

Antitumor Activity, Pathology, Global Phase +17

Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1–3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with <i>FGFR3</i> Alterations

Sumanta K. Pal, Jonathan E. Rosenberg, Jean Hoffman‐Censits et al. · Cancer Discovery · 2018 · 252 citations · Full text