Haihua Xie

A ‘new lease of life’: FnCpf1 possesses DNA cleavage activity for genome editing in human cells

Mengjun Tu, Lin Li, Xiubin He et al. · Nucleic Acids Research · 2017 · 133 citations · Full text

Chromatin, Genome Instability, Functional Genomics +15

SaCas9 Requires 5′‐NNGRRT‐3′ PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells

Haihua Xie, Lianchao Tang, Xiubin He et al. · Biotechnology Journal · 2017 · 67 citations

Molecular Biology, Protein Expression, Human Cells +19

High-fidelity SaCas9 identified by directional screening in human cells

Haihua Xie, Xianglian Ge, Fayu Yang et al. · PLoS Biology · 2020 · 58 citations · Full text

Engineering, Genetics, Molecular Biology +18

Effect of quaternization degree on physiochemical and biological activities of chitosan from squid pens

Jun Huang, Cheng Zhenhua, Haihua Xie et al. · International Journal of Biological Macromolecules · 2014 · 46 citations

Squid Pens, Quaternization Degree, Bioanalysis +7

CRISPR/Cas9- loxP -Mediated Gene Editing as a Novel Site-Specific Genetic Manipulation Tool

Fayu Yang, Changbao Liu, Ding Chen et al. · Molecular Therapy — Nucleic Acids · 2017 · 42 citations · Full text