Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model

Romain Fol, Jérôme Braudeau, Susann Ludewig, +10

Acta Neuropathologica

Synaptic PlasticityNeurodegenerative DiseasesAlzheimer's DiseaseMedicineSynaptic Transmission +8

Dual Plug-and-Display Synthetic Assembly Using Orthogonal Reactive Proteins for Twin Antigen Immunization

Karl D. Brune, Can M. Buldun, Yuanyuan Li, +4

Bioconjugate Chemistry

Modular PlatformEngineeringPeptide EngineeringImmunologyMolecular Biology +19

Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway

Nelli Milosch, Gaye Tanriöver, Arpita Kundu, +12

Cell Death and Disease

Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody

F. Lennartz, Florian Brod, Rebecca A. Dabbs, +11

Nature Communications

Rational development of a protective P. vivax vaccine evaluated with transgenic rodent parasite challenge models

Ahmed M. Salman, Eduardo Montoya-Díaz, Heather C. West, +14

Scientific Reports

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

Torben Schiffner, Natalia de Val, Rebecca A. Russell, +10

Journal of Virology

Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice

Florian Brod, Kazutoyo Miura, Iona J. Taylor, +6

Frontiers in Immunology

Phase I assessments of first-in-human administration of a novel malaria anti-sporozoite vaccine candidate, R21 in matrix-M adjuvant, in UK and Burkinabe volunteers

Navin Venkatraman, Alfred B. Tiono, Georgina Bowyer, +37

West African AdultsMalariaImmunologyImmunodominanceVaccine Surveillance +16

Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice

Katharine A. Collins, Florian Brod, Rebecca Snaith, +8

Scientific Reports

A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis

Panjaporn Chaichana, Narisara Chantratita, Florian Brod, +11

PLoS neglected tropical diseases