The Innate Growth Bistability and Fitness Landscapes of Antibiotic-Resistant Bacteria

J. Barrett Deris, Minsu Kim, Zhongge Zhang, +4

Science

BiologyInnate Growth BistabilityAntimicrobial Resistance GeneAntimicrobial SusceptibilityAntibiotics +9

On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient

Rutger Hermsen, J. Barrett Deris, Terence Hwa

Proceedings of the National Academy of Sciences

Transcriptional Regulation by Competing Transcription Factor Modules

Rutger Hermsen, Sander J. Tans, Pieter Rein ten Wolde

PLoS Computational Biology

A growth‐rate composition formula for the growth of <i>E. coli</i> on co‐utilized carbon substrates

Rutger Hermsen, Hiroyuki Okano, Conghui You, +2

Molecular Systems Biology

Carbon SequestrationEngineeringBiological Carbon FixationGrowth‐rate Composition FormulaMicrobial Physiology +5

The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

Peter C. de Greef, Theres Oakes, Bram Gerritsen, +4

eLife

Adaptive Immune SystemGeneticsT-regulatory CellImmunologyImmune Regulation +24

Regulation underlying hierarchical and simultaneous utilization of carbon substrates by flux sensors in Escherichia coli

Hiroyuki Okano, Rutger Hermsen, Karl Kochanowski, +1

Nature Microbiology

BioenergeticsBacteriologyBioprocess MonitoringEscherichia ColiCarbon Substrates +7

Sources and Sinks: A Stochastic Model of Evolution in Heterogeneous Environments

Rutger Hermsen, Terence Hwa

Physical Review Letters

BiologyEvolution StrategyTheoretical EcologySpatial HeterogeneityNatural Sciences +9

Speed, Sensitivity, and Bistability in Auto-activating Signaling Circuits

Rutger Hermsen, David W. Erickson, Terence Hwa

PLoS Computational Biology

Environmental SignalingEngineeringRapid InductionAnalog DesignMolecular Biology +14

Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain

Michael Sheinman, Ksenia Arkhipova, Peter F. Arndt, +3

eLife

Comparative GenomicsGeneticsIdentical SequencesHgt EventsGenomics +18

Combinatorial Gene Regulation Using Auto-Regulation

Rutger Hermsen, Bas Ursem, Pieter Rein ten Wolde

PLoS Computational Biology

Response FunctionEngineeringGeneticsMolecular BiologyEscherichia Coli +15