Mark E. McDonnell

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

Céline Schalk‐Hihi, Carsten J. Schubert, Richard Alexander et al. · Protein Science · 2011 · 127 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

Troy E. Messick, Garry R. Smith, Samantha S. Soldan et al. · Science Translational Medicine · 2019 · 124 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Discovery of KLS-13019, a Cannabidiol-Derived Neuroprotective Agent, with Improved Potency, Safety, and Permeability

William A. Kinney, Mark E. McDonnell, Hua Zhong et al. · ACS Medicinal Chemistry Letters · 2016 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis and in vitro evaluation of a novel iodinated resiniferatoxin derivative that is an agonist at the human vanilloid VR1 receptor

Mark E. McDonnell, Sui‐Po Zhang, Adrienne E. Dubin et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 40 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Orally Active Benzamide Antipsychotic Agents with Affinity for Dopamine D₂, Serotonin 5-HT_1A, and Adrenergic α₁Receptors

Allen B. Reitz, Ellen W. Baxter, Ellen E. Codd et al. · Journal of Medicinal Chemistry · 1998 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16