Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system

Yuyong Zhou, Karen Anbro Gammeltoft, Line A. Ryberg, +11

Science Advances

Viral Polymerase StructureReverse GeneticsResistance MonitoringViral PathogenesisImmunology +15

Mouse models of acute and chronic hepacivirus infection

Eva Billerbeck, Raphael Wolfisberg, Ulrik Fahnøe, +12

Science

In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

Yuyong Zhou, Kerry Gilmore, Santseharay Ramírez, +10

Scientific Reports

Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication

Santseharay Ramírez, Carlota Fernandez-Antunez, Andrea Galli, +13

Antimicrobial Agents and Chemotherapy

HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models

Long V. Pham, Santseharay Ramírez, Judith M. Gottwein, +4

Gastroenterology

Molecular VirologyHcv Genotype 6APathogenesisViral PathogenesisHepatitis +8

Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 <i>In Vitro</i>

Karen Anbro Gammeltoft, Yuyong Zhou, Carlos R. Duarte Hernandez, +10

Antimicrobial Agents and Chemotherapy

Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro

Yuyong Zhou, Karen Anbro Gammeltoft, Line A. Ryberg, +10

Nirmatrelvir-mpro BindingHealth SciencesEmerging Infectious DiseasesMedicineAntiviral Drug Development +11

HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape

Long V. Pham, Sanne B. Jensen, Ulrik Fahnøe, +9

Journal of Hepatology

Viral ReplicationPathogenesisViral PathogenesisImmunologyAntiviral Drug Development +3

Versatile SARS-CoV-2 Reverse-Genetics Systems for the Study of Antiviral Resistance and Replication

Ulrik Fahnøe, Long V. Pham, Carlota Fernandez-Antunez, +9

Viruses

Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine

Keven Lothert, Anna Offersgaard, Anne Finne Pihl, +7

Scientific Reports

Viral ReplicationSynthetic VirologyImmunologyDownstream ProcessUltrafiltration Techniques +17