21:I[432972,["/_next/static/chunks/bb923814e1f4d2e9.js","/_next/static/chunks/dd3ee9f5b7716ca6.js","/_next/static/chunks/4204a0ae82542ca8.js","/_next/static/chunks/30036bedc5269936.js","/_next/static/chunks/6e1aa89a642f40be.js","/_next/static/chunks/cd5e572bc3e4eb92.js","/_next/static/chunks/8ffd0b71567920d8.js","/_next/static/chunks/67ea6dfd21f16c5f.js","/_next/static/chunks/24eb4379f68013fd.js","/_next/static/chunks/b8cd775ffdf935bd.js","/_next/static/chunks/983103cd9eb7b428.js","/_next/static/chunks/d4ac9dcf27f6ff52.js","/_next/static/chunks/294b9525248c8e5f.js"],"default"] 22:T48e,A glycosylation strategy based on click chemistry was employed to develop a naphthalimide-based Fe³⁺ fluorescent probe with low cytotoxicity and good water-solubility. The selectivity and sensitivity to Fe³⁺ of three synthesized naphthalimide-based fluorescent probes follows a Nap-PZ < Nap-OH < Nap-Glc trend, because Nap-PZ was modified with a good water-soluble group. The cytotoxicity follows a Nap-PZ > Nap-OH > Nap-Glc trend, because the exposed toxic group of Nap-PZ was shielded by a good biocompatible group. The detection limit toward Fe³⁺ ion follows a Nap-PZ (7.40 × 10^-6 M) > Nap-OH (2.73 × 10^-7 M) > Nap-Glc (4.27 × 10^-8 M) trend. Moreover, Nap-Glc could be used to detect Fe³⁺ in living cells. The fluorescent "off-on" response of Nap-Glc towards Fe³⁺ could be recognized by the naked eye, and the "off-on" fluorescent mechanism also was demonstrated by theoretical calculations. Therefore, Nap-Glc is a novel glucosyl naphthalimide fluorescent probe for environmental or biological detection of Fe³⁺ with low cytotoxicity and good water-solubility.

#	Concept	H-Index	Publications	Citations
1	Medicine	1	1	13
2	Natural Sciences	1	1	13
3	Biochemistry	1	1	13
4	Molecular Biology	1	1	13
5	Biophysics	1	1	13

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