Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer

Ignasius Joanito, Pratyaksha Wirapati, Nancy Q. Zhao, +49

Nature Genetics

Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy

Ankur Sharma, Elaine Yiqun Cao, Vibhor Kumar, +15

Nature Communications

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, +22

Nature Communications

Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures

Chayaporn Suphavilai, Shumei Chia, Ankur Sharma, +5

Genome Medicine

A comparative study of tumour-on-chip models with patient-derived xenografts for predicting chemotherapy efficacy in colorectal cancer patients

Louis Jun Ye Ong, Shumei Chia, Stephen Qi Rong Wong, +10

Frontiers in Bioengineering and Biotechnology

Pembrolizumab with or without bevacizumab in platinum-resistant recurrent or metastatic nasopharyngeal carcinoma: a randomised, open-label, phase 2 trial

Wan-Qin Chong, Jia-Li Low, Joshua K. Tay, +19

The Lancet Oncology

Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

Andrea Ravasio, Myint Zu Myaing, Shumei Chia, +16

Communications Biology