Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles

Ming Wang, John A. Zuris, Fantao Meng, +10

Proceedings of the National Academy of Sciences

A multimodal generative AI copilot for human pathology

Ming Y. Lu, Bowen Chen, Drew F. K. Williamson, +17

Nature

Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast

Zhiyi Liu, Dimitra Pouli, Carlo Alonzo, +6

Science Advances

Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

Antonio Varone, Joanna Xylas, Kyle P. Quinn, +7

Cancer Research

Glutamine ConsumptionOptical Redox RatioEngineeringOptogeneticsRedox Biology +18

3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumors

Disha Sood, Min D. Tang‐Schomer, Dimitra Pouli, +10

Nature Communications

Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis

Dimitra Pouli, Mihaela Balu, Carlo Alonzo, +7

Science Translational Medicine

Automated quantification of three-dimensional organization of fiber-like structures in biological tissues

Zhiyi Liu, Dimitra Pouli, Disha Sood, +10

Biomaterials

Tissue EngineeringMechanobiologyThree-dimensional OrganizationTissue ImagingEngineering +12

Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles

Xiaoying Wang, Yamin Li, Quanshun Li, +9

Journal of Controlled Release

Tissue EngineeringEngineeringRnase ANano-drug DeliveryHyaluronic Acid Modification +5

Noninvasive assessment of mitochondrial organization in three-dimensional tissues reveals changes associated with cancer development

Joanna Xylas, Antonio Varone, Kyle P. Quinn, +8

International Journal of Cancer

Mitochondrial BiologyNoninvasive AssessmentMetabolic RemodelingCancer BiologyTumor Biology +18

Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity

Emily Stuntz, Yusi Gong, Disha Sood, +7

Scientific Reports