Frederick C. Streich

Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape

Constance J. Martin, Abhishek Datta, Christopher Littlefield et al. · Science Translational Medicine · 2020 · 223 citations

Capturing a substrate in an activated RING E3/E2–SUMO complex

Frederick C. Streich, Christopher D. Lima · Nature · 2016 · 112 citations · Full text

Natural Sciences, Multi-protein Assembly, Molecular Biology +1

E1-E2 Interactions in Ubiquitin and Nedd8 Ligation Pathways

Zeynep Tokgöz, Thomas J. Siepmann, Frederick C. Streich et al. · Journal of Biological Chemistry · 2011 · 56 citations · Full text

Tripartite Motif Ligases Catalyze Polyubiquitin Chain Formation through a Cooperative Allosteric Mechanism

Frederick C. Streich, Virginia P. Ronchi, J. Patrick Connick et al. · Journal of Biological Chemistry · 2013 · 44 citations · Full text

Polyubiquitin Chain Formation, Protein Assembly, Molecular Regulation +24

Carboxylic acid functionalized cobalt(iii) cyclen complexes for catalytic hydrolysis of phosphodiester bonds

D. Andrew Knight, James B. Delehanty, Ellen R. Goldman et al. · Dalton Transactions · 2004 · 26 citations