Selective Inhibitor of Proteasome's Caspase-like Sites Sensitizes Cells to Specific Inhibition of Chymotrypsin-like Sites

Matthew Britton, Marcella M. Lucas, Sondra L. Downey-Kopyscinski, +10

Chemistry & Biology

Specific InhibitionProtein FunctionSignal TransductionBiochemistryChymotrypsin-like Sites +9

Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2

Feng Rao, Ji-Young Cha, Jing Xu, +11

Molecular Cell

Ck2 PhosphorylationSignal TransductionCell RegulationMolecular RegulationMedicine +11

Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide

Chirag Vasavda, Ruchita Kothari, Adarsha P. Malla, +13

Cell chemical biology

BiochemistryIron MetabolismHeme DegradationHeme SignalingBrain Injury +6

Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity

Samer Singh, Zhiqiang Wang, Dennis Liang Fei, +12

Cancer Research

ImmunologyCell ProliferationCancer BiologyTumor BiologyCell Interaction +14

Hedgehog Signaling Regulates Bladder Cancer Growth and Tumorigenicity

Dennis Liang Fei, Avencia Sánchez-Mejías, Zhiqiang Wang, +15

Cancer Research

UrologyHh ReceptorSignaling PathwayGenitourinary CancerMedicine +7

The Full-length Unprocessed Hedgehog Protein Is an Active Signaling Molecule

Robert Tokhunts, Samer Singh, T. Ming Chu, +11

Journal of Biological Chemistry

The Hedgehog processing pathway is required for NSCLC growth and survival

Jezabel Rodríguez‐Blanco, Neal Schilling, Robert Tokhunts, +16

Oncogene

BiologyHedgehog Processing PathwayDevelopmental BiologyCell DivisionMorphogenesis +3

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions

Xiao Chang, Sally A. Ogle, Michael A. Schumacher, +7

American Journal of Physiology-Gastrointestinal and Liver Physiology

Identification of a Family of Fatty-Acid-Speciated Sonic Hedgehog Proteins, Whose Members Display Differential Biological Properties

Jun Long, Robert Tokhunts, William M. Old, +7

Cell Reports

Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner

Samer Singh, Robert Tokhunts, Valérie Baubet, +7

Human Genetics

Developmental BiologyDominant Negative MannerGenetic DisorderGeneticsSonic Hedgehog Mutations +3