The BosR regulatory protein of <i>Borrelia burgdorferi</i> interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete

Jenny A. Hyde, Dana K. Shaw, Roger Smith, +2

Molecular Microbiology

Bosr MutantImmunologyMolecular BiologyBosr Regulatory ProteinRedox Biology +20

Infection-derived lipids elicit an immune deficiency circuit in arthropods

Dana K. Shaw, Xiaowei Wang, Lindsey J. Brown, +18

Nature Communications

Characterization of a Conditional<i>bosR</i>Mutant in<i>Borrelia burgdorferi</i>

Jenny A. Hyde, Dana K. Shaw, Roger Smith, +2

Infection and Immunity

Host ResponseVirulence Gene ExpressionBorrelia BurgdorferiGeneticsPathogenesis +11

Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection

Adela S. Oliva Chávez, Xiaowei Wang, Liron Marnin, +30

Nature Communications

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation

Xiaowei Wang, Dana K. Shaw, Olivia S. Sakhon, +13

Infection and Immunity

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationTick Proteins +18

p47 licenses activation of the immune deficiency pathway in the tick <i>Ixodes scapularis</i>

Erin E. McClure Carroll, Xiaowei Wang, Dana K. Shaw, +6

Proceedings of the National Academy of Sciences

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

Xiaowei Wang, Dana K. Shaw, Holly Hammond, +16

PLoS Pathogens

Microbial PathogensInnate Immune SystemImmune RegulationImmunologyPathology +27

In Vivo Imaging Demonstrates That Borrelia burgdorferi ospC Is Uniquely Expressed Temporally and Spatially throughout Experimental Infection

Jonathan T. Skare, Dana K. Shaw, Jerome P. Trzeciakowski, +1

PLoS ONE

Vivo ImagingPathogen DetectionImmunologyPathologyBorrelia Burgdorferi Ospc +16

Ticks: More Than Just a Pathogen Delivery Service

Jason M. Park, Adela S. Oliva Chávez, Dana K. Shaw

Frontiers in Cellular and Infection Microbiology

Pathogenic MicrobiologyMicrobial PathogensBacterial PathogensVector-borne PathogenTick-borne Disease +16

Croquemort elicits activation of the immune deficiency pathway in ticks

Anya J. O’Neal, Nisha Singh, Agustín Rolandelli, +18

Proceedings of the National Academy of Sciences