Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia

Quanjun Yang, Jiang‐Rong Zhao, Juan Hao, +8

Journal of Cachexia Sarcopenia and Muscle

Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal α3 glycine receptors

Jingyang Zhang, Nian Gong, Jinlu Huang, +2

Pain

Glycine ReceptorPain TherapyPain DisordersPain MedicineNeuropathic Pain +17

Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat

Hong Wei, Ari Koivisto, Marja Saarnilehto, +6

Pain

Acute PainPain MedicineSynaptic TransmissionNeuropathic PainMolecular Pain +18

A Series of d-Amino Acid Oxidase Inhibitors Specifically Prevents and Reverses Formalin-Induced Tonic Pain in Rats

Nian Gong, Zhenyu Gao, Yanchao Wang, +4

Journal of Pharmacology and Experimental Therapeutics

Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation

Quanjun Yang, Yan Huo, Yonglong Han, +7

Molecular Cancer Therapeutics

Muscle FunctionMurine Cachexia ModelChemoprevention StrategyAkt ActivationErk Inhibition +24

Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study

Quanjun Yang, Genjin Yang, Wan Lili, +7

PLoS ONE

Cardiovascular PharmacologyMetabolomic ProfilingPharmacotherapyPotential BiomarkersCardiovascular Toxicity +17

D2HGDH-mediated D2HG catabolism enhances the anti-tumor activities of CAR-T cells in an immunosuppressive microenvironment

Quanjun Yang, Juan Hao, Mengyi Chi, +11

Molecular Therapy

Matrine improves skeletal muscle atrophy by inhibiting E3 ubiquitin ligases and activating the Akt/mTOR/FoxO3α signaling pathway in C2C12 myotubes and mice

Li Chen, Linlin Chen, Lili Wan, +6

Oncology Reports

Contributions of spinal d-amino acid oxidase to bone cancer pain

Jinlu Huang, Xiaoling Chen, Cheng Guo, +1

Amino Acids

Health SciencesBiochemistryPain MedicineMedicineOsteoarthritis +10

Intrathecal administration of a gap junction decoupler, an inhibitor of Na+–K+–2Cl− cotransporter 1, or a GABAA receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat

Hong Wei, Bin Hao, Jinlu Huang, +4

Pharmacology Biochemistry and Behavior

Pain DisordersPain MedicineSynaptic TransmissionNeuromodulation TherapiesMolecular Pain +15