CACNA1H Mutations in Autism Spectrum Disorders

Igor Splawski, Dana Yoo, Stephanie C. Stotz, +3

Journal of Biological Chemistry

Neurodevelopmental DisordersDevelopmental BiologyBrain DevelopmentAutism Spectrum DisordersGenetics +12

ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice

Alipi V. Naydenov, Eric A. Horne, Christine S. Cheah, +15

Neuron

Ptz-induced SeizuresNeurophysiologyMedicineNeuropharmacologyR6/2 Mice +6

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Yulong Su, Carl Pelz, Tao Huang, +10

Genes & Development

Molecular BiologyTarget GenesNuclear Pore BasketEpigeneticsCellular Physiology +18

Downregulation of cannabinoid receptor 1 from neuropeptide <scp>Y</scp> interneurons in the basal ganglia of patients with Huntington's disease and mouse models

Eric A. Horne, Jonathan Coy, Katie Swinney, +12

European Journal of Neuroscience

Basal GangliaNeurotransmitterSynaptic SignalingCannabinoid PharmacologySocial Sciences +17

ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme

Allison E. Cherry, Brian R. Haas, Alipi V. Naydenov, +15

Molecular Cancer Therapeutics

Current Antitubulin AgentsNeuro-oncologyTumor BiologyTherapeutic PotentialGlioma +13

GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation

Allison E. Cherry, Juan Jesus Vicente, Cong Xu, +4

Glia

CytoskeletonMitotic ProgressionCancer BiologyGliomaTumor Biology +14

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects

Ron Korstanje, Jigar Desai, Gloria Lazar, +10

Physiological Genomics

Vacuolated LensOcular DiseaseGeneticsGpr161 MutationCataract +14

Alkylindole-sensitive receptors modulate microglial cell migration and proliferation

Susan Fung, Allison E. Cherry, Cong Xu, +1

Glia

Dynamic mass redistribution reveals diverging importance of PDZ-ligands for G protein-coupled receptor pharmacodynamics

Nathan D. Camp, Kyung-Soon Lee, Allison E. Cherry, +9

Pharmacological Research

G Protein-coupled ReceptorMedicineFunctional SelectivityPharmacologyReceptor (Biochemistry) +4