Multifunctional biocatalyst for conjugate reduction and reductive amination

Thomas W. Thorpe, James R. Marshall, Vanessa Harawa, +12

Nature

BiocatalysisChemical EngineeringBioconjugationConjugate Reduction

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

Mark Petchey, Aníbal Cuetos, Benjamin Rowlinson, +7

Angewandte Chemie International Edition

EngineeringOrganic ChemistryPharmaceutical ChemistryEnzyme McbaMedicinal Chemistry +14

Simple and quick preparation of α-thiocyanate ketones in hydroalcoholic media. Access to 5-aryl-2-imino-1,3-oxathiolanes

Fabricio R. Bisogno, Aníbal Cuetos, Iván Lavandera, +1

Green Chemistry

Quick PreparationHydroalcoholic MediaSimple PreparationBioorganic ChemistryHeterocyclic +13

Coupling biocatalysis and click chemistry: one-pot two-step convergent synthesis of enantioenriched 1,2,3-triazole-derived diols

Aníbal Cuetos, Fabricio R. Bisogno, Iván Lavandera, +1

Chemical Communications

Access to Enantiopure α‐Alkyl‐β‐hydroxy Esters through Dynamic Kinetic Resolutions Employing Purified/Overexpressed Alcohol Dehydrogenases

Aníbal Cuetos, Ana Rioz‐Martínez, Fabricio R. Bisogno, +5

Advanced Synthesis & Catalysis

E. ColiDerivativesEngineeringBiochemistryAldehyde Dehydrogenase +10

Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β‐Fluoroamines by Formal Tandem Hydrodefluorination/Deamination

Aníbal Cuetos, Marina García‐Ramos, Eva‐Maria Fischereder, +5

Angewandte Chemie International Edition

<i>S</i> ‐Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule <i>C</i> ‐Alkylation

Iain J. W. McKean, Joanna C. Sadler, Aníbal Cuetos, +5

Angewandte Chemie International Edition

Dynamic Kinetic Resolution of α‐Substituted β‐Ketoesters Catalyzed by Baeyer–Villiger Monooxygenases: Access to Enantiopure α‐Hydroxy Esters

Ana Rioz‐Martínez, Aníbal Cuetos, Cristina Rodríguez, +4

Angewandte Chemie International Edition

Enantiopure α‐Hydroxy EstersBaeyer–villiger MonooxygenasesBiochemistryEngineeringNatural Sciences +11

Asymmetric Synthesis of Primary and Secondary β‐Fluoro‐arylamines using Reductive Aminases from Fungi

Daniel González‐Martínez, Aníbal Cuetos, Mahima Sharma, +4

ChemCatChem

Secondary β‐Fluoro‐arylaminesEngineeringOrganic ChemistryChemistryEnzymatic Modification +14

Expanding dynamic kinetic protocols: transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives

Aníbal Cuetos, Iván Lavandera, Vicente Gotor

Chemical Communications

Acyclic α-Alkyl-β-keto EstersDerivativesEngineeringBiochemistryNatural Sciences +10