Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

Baidong Hou, Boris Reizis, Anthony DeFranco

Immunity

InflammationToll-like Receptors-Extrinsic MechanismsAutoimmune DiseaseAdaptive Immune System +10

γδ intraepithelial lymphocytes are essential mediators of host–microbial homeostasis at the intestinal mucosal surface

Anisa S. Ismail, Kari M. Severson, Shipra Vaishnava, +8

Proceedings of the National Academy of Sciences

DysbiosisMicrobial PathogensHost-microbe InteractionsImmunologyImmune Regulation +18

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

Hong Sheng, Zhimin Zhang, Hongtao Liu, +11

Immunity

VaccinationVirus-derived Nanoparticle AntigenAdaptive Immune SystemHumoral ResponseImmunology +11

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis

Gianna Hammer, Emre E. Turer, Kimberly E. Taylor, +12

Nature Immunology

InflammationCytokineImmune HomeostasisAutoimmune DiseaseImmunology +9

Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response

Baidong Hou, Philippe Saudan, Gary Ott, +7

Immunity

Autoimmune DiseaseMyd88 SignalingImmunologyB CellsInnate Immune System +10

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

Megan Raetz, Sun‐Hee Hwang, Cara L. Wilhelm, +10

Nature Immunology

Host ResponseMucosal ImmunologyMicrobial PathogensPaneth CellsPathogenesis +8

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

Shaun W. Jackson, Holly M. Jacobs, Tanvi Arkatkar, +6

The Journal of Experimental Medicine

Germinal CentersAdaptive Immune SystemHumoral ResponseImmunologyImmune Regulation +23

Tumor Necrosis Factor α Activates the Human Plasminogen Activator Inhibitor-1 Gene through a Distal Nuclear Factor κB Site

Baidong Hou, Mesut Eren, Corrie Painter, +4

Journal of Biological Chemistry

CD8 ⁺ T Cell Immune Response in Immunocompetent Mice during Zika Virus Infection

Huarong Huang, Shihua Li, Yongli Zhang, +11

Journal of Virology

Critical coordination of innate immune defense against <i>Toxoplasma gondii</i> by dendritic cells responding via their Toll-like receptors

Baidong Hou, Alicia Benson, Lili Kuzmich, +2

Proceedings of the National Academy of Sciences

Critical CoordinationMicrobial PathogensAdaptive Immune SystemInnate Immune SystemImmune Regulation +21