ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer

Shuohui Dong, Shuo Liang, Zhiqiang Cheng, +10

Journal of Experimental & Clinical Cancer Research

RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

Liang Tao, Yuguo Yi, Yuxin Chen, +13

Cell Death and Differentiation

InflammationSignal TransductionHepatologyRip1 Kinase ActivityLiver Physiology +12

Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA

Xiaoxia Liu, Wei Wang, Dmitry Samarsky, +16

Nucleic Acids Research

In Vivo Gene TherapyVegfr2 Sirna MoleculesImmunologyImmunotherapeuticsGene Delivery +16

Personal thermal comfort models based on physiological measurements – A design of experiments based review

Kai Chen, Qian Xu, Berlynette Leow, +1

Building and Environment

KinesiologyEngineeringPhysiologyThermal ComfortThermodynamics +5

Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells

Sen Wang, Kexin Wang, Chun‐Dong Zhang, +10

Cell Death and Disease

Hepatocyte Adenosine Kinase Promotes Excessive Fat Deposition and Liver Inflammation

Honggui Li, Juan Zheng, Qian Xu, +15

Gastroenterology

ObesityMetabolic SyndromeInflammationLiver InflammationHepatology +13

Interleukin-18 Promoter Gene Polymorphisms in Chinese Patients With Systemic Lupus Erythematosus: Association With CC Genotype at Position –607

Qian Xu, Tin Kyaw, Sivalingam Suppiah Paramalingam, +3

Annals of the Academy of Medicine Singapore

Platelet Changes in Acute Leukemia

Qian Xu, Wenjun Liu

Cell Biochemistry and Biophysics

ThrombopoiesisThrombosisHematological MalignancyBlood PlateletHematology +4

Novel brain reactive autoantibodies: Prevalence in systemic lupus erythematosus and association with psychoses and seizures

Qian Xu, Julian Thumboo, L.Y. Lee, +2

Journal of Neuroimmunology

Autoimmune DiseaseSystemic Lupus ErythematosusPsychiatryLupusMedicine +12

LINC00543 promotes colorectal cancer metastasis by driving EMT and inducing the M2 polarization of tumor associated macrophages

Jinsen Zheng, Rongzhang Dou, Xinyao Zhang, +9

Journal of Translational Medicine