Dynamic programming of CD8+ T lymphocyte responses

Marianne J.B. van Stipdonk, Gijs Hardenberg, Martijn S. Bijker, +4

Nature Immunology

EngineeringAdaptive Immune SystemMedicineImmunologyDynamic Programming +4

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Rinke Bos, Lucy Rutten, Joan E. M. van der Lubbe, +21

npj Vaccines

ImmunologyImmunodominanceImmunotherapeuticsViral Structural ProteinViral Surface Spike +16

Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation

Jenny Hendriks, Lourdes Planelles, J de Jong-Odding, +5

Cell Death and Differentiation

Tumor BiologyMedicineCancer Cell BiologyCancer BiologyCell Biology +2

APRIL promotes B-1 cell-associated neoplasm

Lourdes Planelles, Carla Eponina Carvalho-Pinto, Gijs Hardenberg, +9

Cancer Cell

Tumor BiologyLymphoid NeoplasiaB-1 Cell-associated NeoplasmMalignant DiseasePathology +3

Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets

Joel Montané, Loraine Bischoff, Galina Soukhatcheva, +7

Journal of Clinical Investigation

Ccl22-mediated Treg RecruitmentT-regulatory CellImmunologyImmune RegulationRegulatory T Cells +19

The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization andcross‐linking

Fiona C. Kimberley, Liesbeth van Bostelen, Katherine Cameron, +4

The FASEB Journal

Protein AssemblyGlycobiologyImmunologyMolecular BiologyImmune Regulation +23

Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR‐dependent manner

Gijs Hardenberg, Lourdes Planelles, Carla M. Schwarte, +4

European Journal of Immunology

TLR5 is not required for flagellin-mediated exacerbation of DSS colitis

Sabine Ivison, Megan E. Himmel, Gijs Hardenberg, +3

Inflammatory Bowel Diseases

Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Rinke Bos, Lucy Rutten, Joan E. M. van der Lubbe, +21

ImmunologyImmunodominanceImmunotherapeuticsViral Structural ProteinViral Surface Spike +16

CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance

Joel Montané, Mercè Obach, Sigrid Alvarez, +9

Cell Transplantation

T-regulatory CellImmunologyPancreas TransplantationImmunotherapyGraft Survival +19