Photothermal nanofibres enable safe engineering of therapeutic cells

Ranhua Xiong, Dawei Hua, Jelter Van Hoeck, +22

Nature Nanotechnology

NanomedicineEngineeringNanomaterialsNanobiotechnologyTherapeutic Nanomaterials +4

Nanobody Based Dual Specific CARs

Stijn De Munter, Joline Ingels, Glenn Goetgeluk, +6

International Journal of Molecular Sciences

T Cell TherapyDual SpecificityEngineeringMechanical EngineeringImmunology +17

Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation

Laurens Raes, Stephan Stremersch, Juan C. Fraire, +12

Nano-Micro Letters

The checkpoint for agonist selection precedes conventional selection in human thymus

Greet Verstichel, David Vermijlen, Liesbet Martens, +14

Science Immunology

Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies

Leander Huyghe, Alexander Van Parys, Anje Cauwels, +14

EMBO Molecular Medicine

Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

Stijn De Munter, Alexander Van Parys, Layla Bral, +13

International Journal of Molecular Sciences

EngineeringMechanical EngineeringImmunologyAntigen ProcessingImmunotherapeutics +20

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Sigrid Wahlen, Filip Matthijssens, Wouter Van Loocke, +12

eLife

Cell TherapyLymphocyte DevelopmentImmunologyNk CellsCell Proliferation +18

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline Ingels, Laurenz De Cock, Dieter Stevens, +42

Cell Reports Medicine

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

Yasmine Van Caeneghem, Stijn De Munter, Paola Tieppo, +11

OncoImmunology

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, +22

The Journal of Experimental Medicine

Human ThymusLymphocyte DevelopmentGeneticsImmunologyImmune Regulation +22