A proteomic atlas of senescence-associated secretomes for aging biomarker development

Nathan Basisty, Abhijit Kale, Ok Hee Jeon, +9

PLoS Biology

Proteomic AtlasFunctional GenomicsAgingLongevityMedicine +12

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

Anthony J. Covarrubias, Abhijit Kale, Rosalba Perrone, +28

Nature Metabolism

InflammationCd38+ MacrophagesAgingTissue Nad+ DeclineImmunology +9

Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart

Dao‐Fu Dai, Pabalu P. Karunadharma, Ying Ann Chiao, +9

Aging Cell

Plasma proteomic biomarker signature of age predicts health and life span

Toshiko Tanaka, Nathan Basisty, Giovanna Fantoni, +6

eLife

AgingImmunologyPathologyOlder AgeMediation Analysis +15

Algorithmic assessment of cellular senescence in experimental and clinical specimens

Jaskaren Kohli, Boshi Wang, Simone Brandenburg, +7

Nature Protocols

Lifespan ExtensionEngineeringAgingCell DivisionLongevity +9

Global Proteomics and Pathway Analysis of Pressure-Overload–Induced Heart Failure and Its Attenuation by Mitochondrial-Targeted Peptides

Dao‐Fu Dai, Edward J. Hsieh, Tony Chen, +10

Circulation Heart Failure

Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI

Takuto Chiba, Kevin Peasley, Kasey R. Cargill, +10

Journal of the American Society of Nephrology

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

Ying Ann Chiao, Stephen C. Kolwicz, Nathan Basisty, +9

Aging

Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice

Ying Ann Chiao, Huiliang Zhang, Mariya T. Sweetwyne, +19

eLife

Heart FailureCardiac AgingAgingMitochondrial DysfunctionCardiac Regeneration +17

A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker Development

Nathan Basisty, Abhijit Kale, Ok‐Hee Jeon, +9

AgingMolecular BiologyPathologyBiogerontologyProteomic Atlas +17