Kyle Denton

Loss of Spastin Function Results in Disease-Specific Axonal Defects in Human Pluripotent Stem Cell-Based Models of Hereditary Spastic Paraplegia

Kyle Denton, Ling Lei, Jeremy Grenier et al. · Stem Cells · 2013 · 151 citations · Full text

Peripheral Nerve Injury, Spastin Function Results, Spast Gene +18

Pharmacologic rescue of axon growth defects in a human iPSC model of hereditary spastic paraplegia SPG3A

Peng-Peng Zhu, Kyle Denton, Tyler Mark Pierson et al. · Human Molecular Genetics · 2014 · 66 citations · Full text

Genetics, Cytoskeleton, Cellular Neurobiology +16

Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy

Chong-Chong Xu, Kyle Denton, Zhi-Bo Wang et al. · Disease Models & Mechanisms · 2015 · 66 citations · Full text

Impaired lipid metabolism in astrocytes underlies degeneration of cortical projection neurons in hereditary spastic paraplegia

Yongchao Mou, Yi Dong, Zhen‐Yu Chen et al. · Acta Neuropathologica Communications · 2020 · 51 citations · Full text

Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias

Kyle Denton, Yongchao Mou, Chongchong Xu et al. · Human Molecular Genetics · 2018 · 48 citations · Full text

Spinal Cord Injury, Mitochondrial Function, Hereditary Spastic Paraplegias +15