Thomas Powell

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.

T. Annie T. Fong, Laura K. Shawver, Li Sun et al. · PubMed · 1999 · 1K citations

Novel Synthetic Compound, Chemoprevention Strategy, Pathology +20

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

James W. Huleatt, Valerian Nakaar, Priyanka Desai et al. · Vaccine · 2007 · 385 citations

Vaccination, Cross-protection, Vaccine Development +10

Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity

James W. Huleatt, Andrea R. Jacobs, Jie Tang et al. · Vaccine · 2006 · 293 citations

Vaccination, Toll-like Receptors, Cross-protection +12

A West Nile Virus Recombinant Protein Vaccine That Coactivates Innate and Adaptive Immunity

William F. McDonald, James W. Huleatt, Harald G. Foellmer et al. · The Journal of Infectious Diseases · 2007 · 192 citations

Immunology, Immunodominance, Innate Immunity +17

Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.

Laura K. Shawver, D P Schwartz, E Mann et al. · PubMed · 1997 · 130 citations

Pyrimidine Biosynthesis, Glioma, Chemoprevention Strategy +12