Lindsay K. Klofas

Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in <i>IDH</i> -Mutant Gliomas

Hiroaki Wakimoto, Shota Tanaka, William T. Curry et al. · Clinical Cancer Research · 2014 · 182 citations · Full text

Prevention of premature death and seizures in a Depdc5 mouse epilepsy model through inhibition of mTORC1

Lindsay K. Klofas, Brittany Short, Chengwen Zhou et al. · Human Molecular Genetics · 2020 · 43 citations · Full text

Premature Death, Increased Mtorc1 Activation, Pharmacotherapy +16

Exploring Predictors of Response to Dacomitinib in <i>EGFR</i>-Amplified Recurrent Glioblastoma

S. Andrew, Daniel P. Cahill, David A. Reardon et al. · JCO Precision Oncology · 2020 · 29 citations · Full text

Neuronal modeling of alternating hemiplegia of childhood reveals transcriptional compensation and replicates a trigger-induced phenotype

John P. Snow, Grant Westlake, Lindsay K. Klofas et al. · Neurobiology of Disease · 2020 · 21 citations · Full text

DEPDC5 haploinsufficiency drives increased mTORC1 signaling and abnormal morphology in human iPSC-derived cortical neurons

Lindsay K. Klofas, Brittany Short, John P. Snow et al. · Neurobiology of Disease · 2020 · 20 citations · Full text

Rapamycin Treatment, Depdc5 Haploinsufficiency Drives, Cellular Neurobiology +16