Structure of the connexin 26 gap junction channel at 3.5 Å resolution

Shoji Maeda, So Nakagawa, Michihiro Suga, +4

Nature

Gap Junction ChannelPhysicsNatural SciencesApplied PhysicsMolecular Biology +1

Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule

Atsunori Oshima, Kazutoshi Tani, Yoko Hiroaki, +2

Proceedings of the National Academy of Sciences

Connexin MoleculesMolecular BiologyGap JunctionNeurotransmissionCellular Physiology +19

Atomic structure of the innexin-6 gap junction channel determined by cryo-EM

Atsunori Oshima, Kazutoshi Tani, Yoshinori Fujiyoshi

Nature Communications

Protein SecretionEngineeringMolecular BiologyCytoskeletonLarge Protein Family +15

GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM

Florian Hauer, Christoph Gerle, N. Fischer, +6

Structure

Single-particle Cryo-emNatural SciencesSingle Particle BiophysicsMembrane MicrodomainsMembrane Biology +4

Roles of Met-34, Cys-64, and Arg-75 in the Assembly of Human Connexin 26

Atsunori Oshima, Tomoko Doi, Kaoru Mitsuoka, +2

Journal of Biological Chemistry

Molecular BiologyCytoskeletonHuman Connexin 26Cell JunctionsCellular Physiology +16

Mutation of a Conserved Threonine in the Third Transmembrane Helix of α- and β-Connexins Creates a Dominant-negative Closed Gap Junction Channel

Derek L. Beahm, Atsunori Oshima, Guido Gaietta, +7

Journal of Biological Chemistry

Protein SecretionConserved ThreonineMolecular BiologySingle Point MutationCytoskeleton +21

Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids

Batuujin Burendei, Ruriko Shinozaki, Masakatsu Watanabe, +4

Science Advances

Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids

Maki Kuzuya, Hidemi Hirano, Kenichi Hayashida, +8

Science Signaling

Proteinlipid InteractionMolecular BiologyLipid MovementCellular PhysiologyMembrane Transport +18

Asymmetric Configurations and N-terminal Rearrangements in Connexin26 Gap Junction Channels

Atsunori Oshima, Kazutoshi Tani, Masoud Toloue, +7

Journal of Molecular Biology

Molecular BiologyIon ChannelsChannel ProteinsIntercellular CommunicationAsymmetric Configurations +3

Hexadecameric structure of an invertebrate gap junction channel

Atsunori Oshima, Tomohiro Matsuzawa, Kazuyoshi Murata, +2

Journal of Molecular Biology

Biophysical ModelingInvertebrate-specific Gap JunctionMolecular BiologyCellular PhysiologyBulb Densities +14