Antonio Di Dato

Identification of the First Inhibitor of the GBP1:PIM1 Interaction. Implications for the Development of a New Class of Anticancer Agents against Paclitaxel Resistant Cancer Cells

Mirko Andreoli, Marco Persico, Ajay Kumar et al. · Journal of Medicinal Chemistry · 2014 · 40 citations · Full text

Tumor Biology, Molecular Pharmacology, Pim1 Interaction +15

Cationic porphyrins are tunable gatekeepers of the 20S proteasome

Anna Maria Santoro, Alessandra Cunsolo, Alessandro D’Urso et al. · Chemical Science · 2015 · 31 citations · Full text

New antimalarial 3-methoxy-1,2-dioxanes: optimization of cellular pharmacokinetics and pharmacodynamics properties by incorporation of amino and N-heterocyclic moieties at C4

Dhiraj P. Sonawane, Marco Persico, Yolanda Corbett et al. · RSC Advances · 2015 · 16 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Antiparasitic Agent +16

Electrostatic Map Of Proteasome α-Rings Encodes The Design of Allosteric Porphyrin-Based Inhibitors Able To Affect 20S Conformation By Cooperative Binding

Antonio Di Dato, Alessandra Cunsolo, Marco Persico et al. · Scientific Reports · 2017 · 12 citations · Full text

GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1

Marco Persico, Lella Petrella, Nausicaa Orteca et al. · European Journal of Medicinal Chemistry · 2014 · 11 citations

Gtpase Biology, Protein Function, Signal Transduction +12