W S Chen

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

W S Chen, Katia Manova, Daniel C. Weinstein et al. · Genes & Development · 1994 · 558 citations · Full text

Tissue Development, Developmental Biology, Visceral Endoderm +14

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

Stephen A. Duncan, Katia Manova, W S Chen et al. · Proceedings of the National Academy of Sciences · 1994 · 370 citations · Full text

Genetics, Organ Development, Embryology +16

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

Kleanthis G. Xanthopoulos, Vincent R. Prezioso, W S Chen et al. · Proceedings of the National Academy of Sciences · 1991 · 185 citations · Full text

Genetics, Gene Regulatory Network, Transcriptional Regulation +17