W S Chen

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

W S Chen, Katia Manova, Daniel C. Weinstein et al. · Genes & Development · 1994 · 559 citations · Full text

Life Sciences, Developmental Biology, Genetics +15

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

Stephen A. Duncan, Katia Manova, W S Chen et al. · Proceedings of the National Academy of Sciences · 1994 · 371 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +17

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

Kleanthis G. Xanthopoulos, Vincent R. Prezioso, W S Chen et al. · Proceedings of the National Academy of Sciences · 1991 · 185 citations

Life Sciences, Genetics, Molecular Biology +15