Concepedia
Author
Fadi Rofo
Also Known As
17
Publications
282
Citations
9
H-Index
0
Concepts
All Affiliations
×
All Concepts
8
256
Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta
Fadi Rofo, Jos Buijs, Ronny Falk, +8
Translational Neurodegeneration
2021
46
Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor Circuits
Sharn Perry, Martin Larhammar, Jennifer Vieillard, +6
Journal of Neuroscience
2018
44
Enhanced neprilysin-mediated degradation of hippocampal Aβ42 with a somatostatin peptide that enters the brain
Fadi Rofo, Canan Uğur Yılmaz, Nicole G. Metzendorf, +7
Theranostics
2020
39
A Brain-Targeting Bispecific-Multivalent Antibody Clears Soluble Amyloid-Beta Aggregates in Alzheimer's Disease Mice
Fadi Rofo, Silvio R. Meier, Nicole G. Metzendorf, +5
Neurotherapeutics
2022
33
Blood–brain barrier penetrating neprilysin degrades monomeric amyloid-beta in a mouse model of Alzheimer’s disease
Fadi Rofo, Nicole G. Metzendorf, Cristina Saubi, +5
Alzheimer s Research & Therapy
32
Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer’s Disease Following Treatment with a Brain-Targeting Somatostatin Peptide
Fadi Rofo, Friederike A. Sandbaumhüter, Aikaterini Chourlia, +6
ACS Chemical Neuroscience
21
A single‐chain fragment constant design enables easy production of a monovalent blood–brain barrier transporter and provides an improved brain uptake at elevated doses
Jamie I. Morrison, Nicole G. Metzendorf, Fadi Rofo, +2
Journal of Neurochemistry
2023
Standardized Preclinical <i>In Vitro</i> Blood–Brain Barrier Mouse Assay Validates Endocytosis-Dependent Antibody Transcytosis Using Transferrin-Receptor-Mediated Pathways
Jamie I. Morrison, Alex Petrovic, Nicole G. Metzendorf, +4
Molecular Pharmaceutics
20
Page 1