Rhema M. James

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Ryan Choi, Mowei Zhou, Roger Shek et al. · PLoS ONE · 2021 · 49 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +16

3D-Scaffold: A Deep Learning Framework to Generate 3D Coordinates of Drug-like Molecules with Desired Scaffolds

Rajendra P. Joshi, Niklas W. A. Gebauer, Mridula Bontha et al. · The Journal of Physical Chemistry B · 2021 · 48 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +15

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

Ryan Choi, Mowei Zhou, Roger Shek et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 15 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +15