Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

Zhiduan Su, James G. Burchfield, Pengyi Yang, +21

Nature Communications

Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry

Marin E. Nelson, Benjamin L. Parker, James G. Burchfield, +14

The EMBO Journal

Muscle PhysiologyMuscle FunctionKinesiologyMolecular PhysiologySignal Transduction +13

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

Alison L. Kearney, Dougall M. Norris, Milad Ghomlaghi, +12

eLife

Insulin ReceptorCellular PhysiologyInsulin SignalingSignaling PathwayMetabolic Signaling +14

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Alice Williamson, Dougall M. Norris, Xianyong Yin, +112

Nature Genetics

Genome-wide Association StudyMetabolic SyndromeFunctional GenomicsGeneticsDiabetes +9

Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance

Daniel J. Fazakerley, Julian van Gerwen, Kristen C. Cooke, +13

Nature Communications

Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes

Alison L. Kearney, Kristen C. Cooke, Dougall M. Norris, +5

Journal of Biological Chemistry

Limited oxygen in standard cell culture alters metabolism and function of differentiated cells

Joycelyn Tan, Sam Virtue, Dougall M. Norris, +27

The EMBO Journal

An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction

Dougall M. Norris, Pengyi Yang, James R. Krycer, +3

Journal of Cell Science

Molecular BiologyGene Regulatory NetworkCellular PhysiologyInsulin SignalingSignaling Pathway +20

Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression

Dougall M. Norris, Pengyi Yang, Sung‐Young Shin, +8

iScience

EngineeringIntercellular HeterogeneityGene Regulatory NetworkCellular PhysiologyInsulin Signaling +21

Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate

Xiaowen Duan, Dougall M. Norris, Sean J. Humphrey, +10

Biochemical Journal

Cellular PhysiologyInsulin SignalingSignaling PathwayReceptor Tyrosine KinaseGsk3 Substrate +14