Tomoyuki Mukai

TNF-α inhibits BMP-induced osteoblast differentiation through activating SAPK/JNK signaling

Tomoyuki Mukai, Fumio Otsuka, Hiroyuki Otani et al. · Biochemical and Biophysical Research Communications · 2007 · 140 citations

Medicine, Oral Biology, Bone Metabolism +11

Simvastatin antagonizes tumor necrosis factor-α inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway

Misuzu Yamashita, Fumio Otsuka, Tomoyuki Mukai et al. · Journal of Endocrinology · 2008 · 118 citations · Full text

Medicine, Cell Biology, Pharmacology +17

Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling

Misuzu Yamashita, Fumio Otsuka, Tomoyuki Mukai et al. · Regulatory Peptides · 2010 · 88 citations

Medicine, Cell Biology, Pharmacology +14

SH3BP2 Cherubism Mutation Potentiates TNF-α–Induced Osteoclastogenesis via NFATc1 and TNF-α–Mediated Inflammatory Bone Loss

Tomoyuki Mukai, Shu Ishida, Remi Ishikawa et al. · Journal of Bone and Mineral Research · 2014 · 62 citations · Full text

Medicine, Molecular Genetics, Pathobiology +17

Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-α in C2C12 cells

Yoshinori Matsumoto, Fumio Otsuka, Mariko Takano et al. · Molecular and Cellular Endocrinology · 2010 · 62 citations

Medicine, Cell Biology, Endocrinology +14