Ben de Kruijff

Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

Eefjan Breukink, I. Wiedemann, Cindy van Kraaij et al. · Science · 1999 · 805 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Specific Binding of Nisin to the Peptidoglycan Precursor Lipid II Combines Pore Formation and Inhibition of Cell Wall Biosynthesis for Potent Antibiotic Activity

Imke Wiedemann, Eefjan Breukink, Cindy van Kraaij et al. · Journal of Biological Chemistry · 2001 · 775 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. III. Molecular structure of the polyene antibiotic-cholesterol complexes

Ben de Kruijff, R.A. Demel · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1974 · 609 citations

Life Sciences, Biochemistry, Microbiology +16

The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics

Shang‐Te Danny Hsu, Eefjan Breukink, Eugene Tischenko et al. · Nature Structural & Molecular Biology · 2004 · 544 citations · Full text

Life Sciences, Biochemistry, Microbiology +12

An Alternative Bactericidal Mechanism of Action for Lantibiotic Peptides That Target Lipid II

Hester E. Hasper, Naomi E. Kramer, Leif Smith et al. · Science · 2006 · 497 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17